POST-THYROIDECTOMY THYROTOXICOSIS
Identifieur interne : 002985 ( Main/Exploration ); précédent : 002984; suivant : 002986POST-THYROIDECTOMY THYROTOXICOSIS
Auteurs : W. J. Kalk [Afrique du Sud] ; Shirley Kantor [Afrique du Sud] ; D. Durbach [Afrique du Sud] ; J. Levin [Afrique du Sud]Source :
- The Lancet [ 0140-6736 ] ; 1978.
English descriptors
- Teeft :
- Archs surg, Early recurrences, Euthyroid, Euthyroid patients, Goitre, Goitre size, Goitre weight, Hyperthyroidism, Hypothyroid, Hypothyroidism, Influenza, Johannesburg hospital, Large remnants, Moderate epidemic, Permanent hypothyroidism, Postoperative, Radioiodine, Radioiodine therapy, Recurrence, Recurrent, Recurrent goitres, Recurrent hyperthyroidism, Recurrent thyrotoxicosis, Remnant, Significant incidence, Surg, Therapeutic dose, Thyroid function, Thyroid remnants, Thyroid scan, Thyrotoxicosis, True incidence, Years postoperatively, Young adults.
Abstract
Abstract: 94 patients with postoperative recurrent hyperthyroidism were evaluated for duration of remission, goitre size, and response to radio-iodine (131I). 6 patients required 131I therapy within twelve months of operation—5 had large remnants because of inadequate surgery. 57% of patients relapsed within 5 years, but 16% relapsed after 20 years and 8% after more than 30 years. Estimated goitre weights ranged from 4 g to 65 g, and goitre size was unrelated to the duration of remission. All patients were treated with 131I. 23% of the patients became hypothyroid in the first postoperative year and 10% in the second year. The results indicate that postoperative thyrotoxicosis can recur decades after operation. Operation seems to sensitise the thyroid to the early effects of radiation by 131I.
Url:
DOI: 10.1016/S0140-6736(78)90067-3
Affiliations:
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J." last="Kalk">W. J. Kalk</name><affiliation wicri:level="1"><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Departments of Medicine, Radiotherapy, and Nuclear Medicine, University of the Witwatersrand and Johannesburg Hospital, Johannesburg</wicri:regionArea><wicri:noRegion>Johannesburg</wicri:noRegion></affiliation></author><author><name sortKey="Kantor, Shirley" sort="Kantor, Shirley" uniqKey="Kantor S" first="Shirley" last="Kantor">Shirley Kantor</name><affiliation wicri:level="1"><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Departments of Medicine, Radiotherapy, and Nuclear Medicine, University of the Witwatersrand and Johannesburg Hospital, Johannesburg</wicri:regionArea><wicri:noRegion>Johannesburg</wicri:noRegion></affiliation></author><author><name sortKey="Durbach, D" sort="Durbach, D" uniqKey="Durbach D" first="D." last="Durbach">D. Durbach</name><affiliation wicri:level="1"><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Departments of Medicine, Radiotherapy, and Nuclear Medicine, University of the Witwatersrand and Johannesburg Hospital, Johannesburg</wicri:regionArea><wicri:noRegion>Johannesburg</wicri:noRegion></affiliation></author><author><name sortKey="Levin, J" sort="Levin, J" uniqKey="Levin J" first="J." last="Levin">J. Levin</name><affiliation wicri:level="1"><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Departments of Medicine, Radiotherapy, and Nuclear Medicine, University of the Witwatersrand and Johannesburg Hospital, Johannesburg</wicri:regionArea><wicri:noRegion>Johannesburg</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">The Lancet</title><title level="j" type="abbrev">LANCET</title><idno type="ISSN">0140-6736</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1978">1978</date><biblScope unit="volume">311</biblScope><biblScope unit="issue">8059</biblScope><biblScope unit="page" from="291">291</biblScope><biblScope unit="page" to="294">294</biblScope></imprint><idno type="ISSN">0140-6736</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0140-6736</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Archs surg</term><term>Early recurrences</term><term>Euthyroid</term><term>Euthyroid patients</term><term>Goitre</term><term>Goitre size</term><term>Goitre weight</term><term>Hyperthyroidism</term><term>Hypothyroid</term><term>Hypothyroidism</term><term>Influenza</term><term>Johannesburg hospital</term><term>Large remnants</term><term>Moderate epidemic</term><term>Permanent hypothyroidism</term><term>Postoperative</term><term>Radioiodine</term><term>Radioiodine therapy</term><term>Recurrence</term><term>Recurrent</term><term>Recurrent goitres</term><term>Recurrent hyperthyroidism</term><term>Recurrent thyrotoxicosis</term><term>Remnant</term><term>Significant incidence</term><term>Surg</term><term>Therapeutic dose</term><term>Thyroid function</term><term>Thyroid remnants</term><term>Thyroid scan</term><term>Thyrotoxicosis</term><term>True incidence</term><term>Years postoperatively</term><term>Young adults</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: 94 patients with postoperative recurrent hyperthyroidism were evaluated for duration of remission, goitre size, and response to radio-iodine (131I). 6 patients required 131I therapy within twelve months of operation—5 had large remnants because of inadequate surgery. 57% of patients relapsed within 5 years, but 16% relapsed after 20 years and 8% after more than 30 years. Estimated goitre weights ranged from 4 g to 65 g, and goitre size was unrelated to the duration of remission. All patients were treated with 131I. 23% of the patients became hypothyroid in the first postoperative year and 10% in the second year. The results indicate that postoperative thyrotoxicosis can recur decades after operation. Operation seems to sensitise the thyroid to the early effects of radiation by 131I.</div></front></TEI><affiliations><list><country><li>Afrique du Sud</li></country></list><tree><country name="Afrique du Sud"><noRegion><name sortKey="Kalk, W J" sort="Kalk, W J" uniqKey="Kalk W" first="W. J." last="Kalk">W. J. Kalk</name></noRegion><name sortKey="Durbach, D" sort="Durbach, D" uniqKey="Durbach D" first="D." last="Durbach">D. Durbach</name><name sortKey="Kantor, Shirley" sort="Kantor, Shirley" uniqKey="Kantor S" first="Shirley" last="Kantor">Shirley Kantor</name><name sortKey="Levin, J" sort="Levin, J" uniqKey="Levin J" first="J." last="Levin">J. 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